Detrimental Effects of Diabetes Mellitus on Dental Pulp Elements of Albino Rats.

Diabetes Mellitus (DM) is a group of metabolic disorders with relative or absolute insufficiency insulin secretion and/or concomitant resistance to the action on target tissues. Aim: evaluate effect STZ-induced-DM dental pulp albino rats histologically and ultra-structurally, its pulpal TB Sub-group B1 B2 where animals were sacrificed 2 4 weeks after establishment DM respectively. permanent molars each rat split for detachment, processed histological, immuno-histochemical ultra-structural examination. Results: H&E-stained sections tissue 2-weeks-diabetic showed degenerative changes. Ultra -structural examination changes affecting elements. Immuno-histochemical less T&B lymphocytes. Conclusion: led elements namely, cells, fibers, nerves, vessels. also affected